Antibiotic Resistance Gene Markers
Advanced molecular assay for the detection of clinically relevant antibiotic resistance genes to guide optimal antimicrobial therapy.
Genes Detected
Carbapenemases: KPC, VIM, NDM, IMP, OXA-48-like
Methicillin resistance: mecA, mecC
Vancomycin resistance: VanA, VanB
Extended Spectrum Beta-Lactamase (ESBL): CTX
Sulfonamide resistance: Sul1, Sul2
Trimethoprim resistance: DfrA
Quinolone resistance: QNR
Specimen Type
Urine, wound swab, respiratory sample, or cultured isolate
Methodology
Multiplex PCR assay validated under CLIA (#10D2324831)
Detects gene-specific DNA fragments (amplicons) associated with resistance mechanisms
Turnaround Time
Results available within 24 hours
Clinical Significance
Identifies resistance mechanisms rapidly to inform precision antibiotic therapy and reduce treatment failure.
Limitations
Does not detect all resistance mechanisms.
Detection limited to known gene sequences.
False negatives may occur if gene variants are below detection or mutated.
Disclaimer
Testing performed by Lighthouse Labs, LLC, CLIA #10D2324831, Jacksonville, FL.
Not FDA-approved; validated under CLIA for diagnostic use.
Results should be interpreted by a licensed clinician in conjunction with clinical findings.